Lefamulin(BC-3781)

产品编号: DC8172 Featured
Lefamulin(BC-3781)
结构式
1061337-51-6
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中国地区超过5000个高品质化合物库存
应用领域
Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow.
Cas No.: 1061337-51-6
名称: (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propano-3aH-cyclopenta[8]annulen-8-yl {[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetate
别名: BC-3781,BC 3781,BC3781
SMILES: O=C(O[C@H]1[C@@]([C@H](C)CC2)(C)[C@@](C(CC3)=O)([H])[C@]32[C@@H](C)[C@H](O)[C@](C)(C=C)C1)CS[C@H]4[C@H](O)C[C@H](N)CC4
分子式: C28H45NO5S
分子量: 507.3
纯度: >98%
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow. Lefamulin acts by binding to the peptidyl transferase center, or PTC, on the bacterial ribosome in such a way that it interferes with the interaction of protein production at two key sites known as the “A” site and the “P” site, resulting in the inhibition of bacterial proteins and the cessation of bacterial growth. Lefamulin’s binding occurs with high affinity, high specificity and at molecular sites that are different than other antibiotic classes. For the detailed information of Lefamulin(BC-3781), the solubility of Lefamulin(BC-3781) in water, the solubility of Lefamulin(BC-3781) in DMSO, the solubility of Lefamulin(BC-3781) in PBS buffer, the animal experiment (test) of Lefamulin(BC-3781), the cell expriment (test) of Lefamulin(BC-3781), the in vivo, in vitro and clinical trial test of Lefamulin(BC-3781), the EC50, IC50,and affinity,of Lefamulin(BC-3781), For the detailed information of Lefamulin(BC-3781), the solubility of Lefamulin(BC-3781) in water, the solubility of Lefamulin(BC-3781) in DMSO, the solubility of Lefamulin(BC-3781) in PBS buffer, the animal experiment (test) of Lefamulin(BC-3781), the cell expriment (test) of Lefamulin(BC-3781), the in vivo, in vitro and clinical trial test of Lefamulin(BC-3781), the EC50, IC50,and affinity,of Lefamulin(BC-3781), Please contact DC Chemicals.
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MSDS
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