c-Di-AMP sodium salt

产品编号: DC10481 Featured
c-Di-AMP sodium salt
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环二腺苷酸 c-di-AMP (Cyclic diadenylate) 钠盐
Cas No.:
名称: 3',5'-Cyclic diadenylic acid sodium salt
SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C6N=CN=C7N)O)OP(=O)(O1)[O-])[O-].[Na+].[Na+]
分子式: C20H22N10Na2O12P2
分子量: 702.38
纯度: >98%
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: c-di-AMP is a bacterial secondary messenger. c-di-AMP acts as a potent mucosal adjuvant stimulating both humoral and cellular responses. Endogenous STING and DDX41 agonist; mediates DDX41-STING interaction. Activates STING-dependent IFN-β production in mouse and human cells. Also A2A inverse agonist. Selectively induces apoptosis of monocytes in human PBMC cultures and in NSG mice transplanted with human CD34+ cells.
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