Disodium (R)-2-Hydroxyglutarate 产品说明书 Chemicals
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产品编号 DC8385
名称 Disodium (R)-2-Hydroxyglutarate

化学性质

CAS 103404-90-6
分子式 C5H6NA2O5
分子量 192.08
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


In U-87MG cells, (R)-2-Hydroxyglutarate acts as weak antagonists of α-KG to inhibit α-KG-dependent histone demethylases and increases dimethylation on both H3K9 and H3K79. Besides, (R)-2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling, and thus causes growth arrest and tumor cell killing. For the detailed information of Disodium (R)-2-Hydroxyglutarate, the solubility of Disodium (R)-2-Hydroxyglutarate in water, the solubility of Disodium (R)-2-Hydroxyglutarate in DMSO, the solubility of Disodium (R)-2-Hydroxyglutarate in PBS buffer, the animal experiment (test) of Disodium (R)-2-Hydroxyglutarate, the cell expriment (test) of Disodium (R)-2-Hydroxyglutarate, the in vivo, in vitro and clinical trial test of Disodium (R)-2-Hydroxyglutarate, the EC50, IC50,and affinity,of Disodium (R)-2-Hydroxyglutarate, For the detailed information of Disodium (R)-2-Hydroxyglutarate, the solubility of Disodium (R)-2-Hydroxyglutarate in water, the solubility of Disodium (R)-2-Hydroxyglutarate in DMSO, the solubility of Disodium (R)-2-Hydroxyglutarate in PBS buffer, the animal experiment (test) of Disodium (R)-2-Hydroxyglutarate, the cell expriment (test) of Disodium (R)-2-Hydroxyglutarate, the in vivo, in vitro and clinical trial test of Disodium (R)-2-Hydroxyglutarate, the EC50, IC50,and affinity,of Disodium (R)-2-Hydroxyglutarate, Please contact DC Chemicals.
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