2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
SRT2104 reduces p65/RelA acetylation levels in C2C12 cells.In male C57BL/6J mice, SRT2104 (100 mg/kg, p.o.) extends both mean and maximal lifespan of mice fed a standard diet, and enhances motor coordination, bone mineral density, and insulin sensitivity and decreased inflammation. Short-term SRT2104 treatment preserves bone and muscle mass in an experimental model of atrophy. In Male N171-82Q HD mice, SRT2104 (diet containing 0.5% SRT2104) effectively penetrates the blood-brain barrier, attenuates brain atrophy, improves motor function, and extends survival. For the detailed information of SRT2104 (GSK2245840), the solubility of SRT2104 (GSK2245840) in water, the solubility of SRT2104 (GSK2245840) in DMSO, the solubility of SRT2104 (GSK2245840) in PBS buffer, the animal experiment (test) of SRT2104 (GSK2245840), the cell expriment (test) of SRT2104 (GSK2245840), the in vivo, in vitro and clinical trial test of SRT2104 (GSK2245840), the EC50, IC50,and affinity,of SRT2104 (GSK2245840), For the detailed information of SRT2104 (GSK2245840), the solubility of SRT2104 (GSK2245840) in water, the solubility of SRT2104 (GSK2245840) in DMSO, the solubility of SRT2104 (GSK2245840) in PBS buffer, the animal experiment (test) of SRT2104 (GSK2245840), the cell expriment (test) of SRT2104 (GSK2245840), the in vivo, in vitro and clinical trial test of SRT2104 (GSK2245840), the EC50, IC50,and affinity,of SRT2104 (GSK2245840), Please contact DC Chemicals.
