S-2238(Thrombin Substrate) 产品说明书 Chemicals
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产品编号 DC9807
名称 S-2238(Thrombin Substrate)

化学性质

CAS 115388-96-0
分子式 H-D-PHE-PIP-ARG-PNA.2HCL
分子量 625.6
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


S-2238, which is specific to thrombin, is a short peptide covalently bound to pNA (4-nitroaniline). When attacked by thrombin, it gives up a free pNA which could be detected by a spectrophotometer at 405 nm.S-2238 is mainly used in anti-FIIa activity assay of heparin.S-2238 can be used in many applications, such as: Anti-factor Xa activity to anti-factor IIa activity ratios of heparin and LMWHs. Anti-factor IIa activities of heparin and LMWHs. Activities of antithrombin and thrombin. Anti-factor IIa activities of heparin and LMWHs in human plasma. Production of kits for automated blood analyzers. Evaluation of potential anticoagulants from chemical synthesis, bacterial fermentation and animal tissues.
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