2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Eliprodil is a non-competitive NMDA receptor antagonist which acts at the polyamine modulatory site. Eliprodil is selective for NMDA epsilon 2 (NR2B-containing receptors) over NR2A- and NR2C-containing receptors (IC50 values are 1, > 100 and > 100 μM respectively) in addition to acting as a Sigma Receptor (σ1 ligand) (Ki = 0.013 μM). Eliprodil antagonizes neuronal voltage-gated Ca2+ channels and selectively inhibits the rapid component of the delayed rectifier K+ current (IKr). Furthermore, Eliprodil is reported to act as a neuroprotective. For the detailed information of Eliprodil, the solubility of Eliprodil in water, the solubility of Eliprodil in DMSO, the solubility of Eliprodil in PBS buffer, the animal experiment (test) of Eliprodil, the cell expriment (test) of Eliprodil, the in vivo, in vitro and clinical trial test of Eliprodil, the EC50, IC50,and affinity,of Eliprodil, For the detailed information of Eliprodil, the solubility of Eliprodil in water, the solubility of Eliprodil in DMSO, the solubility of Eliprodil in PBS buffer, the animal experiment (test) of Eliprodil, the cell expriment (test) of Eliprodil, the in vivo, in vitro and clinical trial test of Eliprodil, the EC50, IC50,and affinity,of Eliprodil, Please contact DC Chemicals.
