Ravidasvir free base 产品说明书 Chemicals
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产品编号 DC21526
名称 Ravidasvir free base

化学性质

CAS 1242087-93-9
分子式 C42H50N8O6
分子量 762.91
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description 拉维达韦 Carbamic acid, N-[(1S)-1-[[(2S)-2-[5-[6-[2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1H-benzimidazol-6-yl]-2-naphthalenyl]-1H-imidazol-2-yl]-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-, methyl ester
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Ravidasvir (PPI-668;BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay; has been well tolerated and shown high sustained viral response rates as a key component in all-oral combination regimens in multiple human clinical trials.HCV InfectionPhase 3 Clinical
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