Dyngo-4a 产品说明书 Chemicals
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产品编号 DC8396
名称 Dyngo-4a

化学性质

CAS 1256493-34-1
分子式 C18H14N2O5
分子量 338.31
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Dyngo-4a inhibits dynamin-dependent endocytosis of transferrin in multiple cell types with IC₅₀ of 5.7 μM, and reduces synaptic vesicle endocytosis and activity-dependent bulk endocytosis in cultured neurons and synaptosomes. In motor nerve terminals and cultured hippocampal neurons, Dyngo-4a blocks Alexa Fluor 488-BoNT/A-Hc internalization. In Drosophila S2R+ cells, Dyngo-4a causes a decrease in the level of Armadillo/β-catenin. For the detailed information of Dyngo-4a, the solubility of Dyngo-4a in water, the solubility of Dyngo-4a in DMSO, the solubility of Dyngo-4a in PBS buffer, the animal experiment (test) of Dyngo-4a, the cell expriment (test) of Dyngo-4a, the in vivo, in vitro and clinical trial test of Dyngo-4a, the EC50, IC50,and affinity,of Dyngo-4a, For the detailed information of Dyngo-4a, the solubility of Dyngo-4a in water, the solubility of Dyngo-4a in DMSO, the solubility of Dyngo-4a in PBS buffer, the animal experiment (test) of Dyngo-4a, the cell expriment (test) of Dyngo-4a, the in vivo, in vitro and clinical trial test of Dyngo-4a, the EC50, IC50,and affinity,of Dyngo-4a, Please contact DC Chemicals.
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