2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Spautin 1 is an inhibitor of autophagy; inhibits USP10 and USP13 activity (IC50 values are 0.6 and 0.7 μM respectively) and promotes degradation of Vps34 (class III PI 3-kinase) complexes. Selectively promotes apoptosis of cancer cells under starvation conditions. Prevents the PDGF-induced conversion from the contractile to synthetic phenotype in vascular smooth muscle cells. For the detailed information of Spautin 1, the solubility of Spautin 1 in water, the solubility of Spautin 1 in DMSO, the solubility of Spautin 1 in PBS buffer, the animal experiment (test) of Spautin 1, the cell expriment (test) of Spautin 1, the in vivo, in vitro and clinical trial test of Spautin 1, the EC50, IC50,and affinity,of Spautin 1, For the detailed information of Spautin 1, the solubility of Spautin 1 in water, the solubility of Spautin 1 in DMSO, the solubility of Spautin 1 in PBS buffer, the animal experiment (test) of Spautin 1, the cell expriment (test) of Spautin 1, the in vivo, in vitro and clinical trial test of Spautin 1, the EC50, IC50,and affinity,of Spautin 1, Please contact DC Chemicals.
