2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
In HEK293 cells, MI-3 accesses the protein target and effectively inhibits the menin-MLL-AF9 interaction. MI-3 effectively blocks MLL fusion protein-mediated leukemic transformation by downregulating the expression of target genes required for MLL fusion protein oncogenic activity. In human MLL leukemia cell lines harboring different MLL translocations, MI-3 effectively blocks cell proliferation, and induces apoptosis. For the detailed information of MI-3 (Menin-MLL Inhibitor), the solubility of MI-3 (Menin-MLL Inhibitor) in water, the solubility of MI-3 (Menin-MLL Inhibitor) in DMSO, the solubility of MI-3 (Menin-MLL Inhibitor) in PBS buffer, the animal experiment (test) of MI-3 (Menin-MLL Inhibitor), the cell expriment (test) of MI-3 (Menin-MLL Inhibitor), the in vivo, in vitro and clinical trial test of MI-3 (Menin-MLL Inhibitor), the EC50, IC50,and affinity,of MI-3 (Menin-MLL Inhibitor), For the detailed information of MI-3 (Menin-MLL Inhibitor), the solubility of MI-3 (Menin-MLL Inhibitor) in water, the solubility of MI-3 (Menin-MLL Inhibitor) in DMSO, the solubility of MI-3 (Menin-MLL Inhibitor) in PBS buffer, the animal experiment (test) of MI-3 (Menin-MLL Inhibitor), the cell expriment (test) of MI-3 (Menin-MLL Inhibitor), the in vivo, in vitro and clinical trial test of MI-3 (Menin-MLL Inhibitor), the EC50, IC50,and affinity,of MI-3 (Menin-MLL Inhibitor), Please contact DC Chemicals.
