2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).Preparation of fused bicyclic 2,4-diaminopyrimidine derivatives as a dual ALK and FAK inhibitor
By Jacobs, Martin J.; Ott, Gregory R.
From PCT Int. Appl. (2013), WO 2013134353 A1 20130912. For the detailed information of CEP-37440, the solubility of CEP-37440 in water, the solubility of CEP-37440 in DMSO, the solubility of CEP-37440 in PBS buffer, the animal experiment (test) of CEP-37440, the cell expriment (test) of CEP-37440, the in vivo, in vitro and clinical trial test of CEP-37440, the EC50, IC50,and affinity,of CEP-37440, Please contact DC Chemicals.
