Flavopiridol 产品说明书 Chemicals
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产品编号 DC2014
名称 Flavopiridol

化学性质

CAS 146426-40-6
分子式 C21H20CLNO5
分子量 401.84
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) For the detailed information about the solubility of Flavopiridol in water, the solubility of Flavopiridol in DMSO, the solubility of Flavopiridol in PBS buffer, the animal experiment(test) of Flavopiridol,the in vivo,in vitro and clinical trial test of Flavopiridol,the cell experiment(test) of Flavopiridol,the IC50, EC50 and Affinity of Flavopiridol, please contact DC Chemicals.
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