Dibutyryl-cAMP (Bucladesine) 产品说明书 Chemicals
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产品编号 DC8394
名称 Dibutyryl-cAMP (Bucladesine)

化学性质

CAS 16980-89-5
分子式 C18H23N5NAO8P
分子量 491.37
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Dibutyryl-cAMP inhibits neuronal glucose uptake via PKA activation. In cultured rat hepatocytes, Dibutyryl-cAMP inhibits inducible nitric oxide synthase expression and NF-kappaB-binding activity. Dibutyryl-cAMP also suppress TNFalpha-induced hepatocyte apoptosis by inhibiting FADD up-regulation. In a mouse model, bucladesine (600 nM/mouse, i.p.) reverses zinc chloride- and lead acetate-induced avoidance memory retention impairments. For the detailed information of Dibutyryl-cAMP (Bucladesine), the solubility of Dibutyryl-cAMP (Bucladesine) in water, the solubility of Dibutyryl-cAMP (Bucladesine) in DMSO, the solubility of Dibutyryl-cAMP (Bucladesine) in PBS buffer, the animal experiment (test) of Dibutyryl-cAMP (Bucladesine), the cell expriment (test) of Dibutyryl-cAMP (Bucladesine), the in vivo, in vitro and clinical trial test of Dibutyryl-cAMP (Bucladesine), the EC50, IC50,and affinity,of Dibutyryl-cAMP (Bucladesine), For the detailed information of Dibutyryl-cAMP (Bucladesine), the solubility of Dibutyryl-cAMP (Bucladesine) in water, the solubility of Dibutyryl-cAMP (Bucladesine) in DMSO, the solubility of Dibutyryl-cAMP (Bucladesine) in PBS buffer, the animal experiment (test) of Dibutyryl-cAMP (Bucladesine), the cell expriment (test) of Dibutyryl-cAMP (Bucladesine), the in vivo, in vitro and clinical trial test of Dibutyryl-cAMP (Bucladesine), the EC50, IC50,and affinity,of Dibutyryl-cAMP (Bucladesine), Please contact DC Chemicals.
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