Pelitinib (EKB-569; WAY-EKB 569) 产品说明书 Chemicals
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产品编号 DC7225
名称 Pelitinib (EKB-569; WAY-EKB 569)

化学性质

CAS 257933-82-7
分子式 C24H23CLFN5O2
分子量 467.92
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Pelitinib displays much higher inhibitory activity against EGFR, compared with the closely related c-erbB-2, as well as other kinases such as Src, Cdk4, c-Met, Raf, and MEK/ERK, with IC50 ranging from 282 nM For Src to >20 μM For Cdk4. Consistently, Pel
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