2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process.in vitro: OAC1 enhances the formation of Oct4-GFP+ colonies and accelerates the dynamics of reprogramming. OAC1 enhanced reprogramming efficiency through a mechanism that is independent of endogenous Oct4 promoter demethylation. OAC1 enhanced reprogramming efficiency through a mechanism that is distinct from suppressing p53-p21 expression. Luciferase assay revealed that OAC1 had no effect on Topflash activity, although BIO activated the Topflash reporter potently. OAC1 functions through a mechanism that is independent of the Wnt signaling. For the detailed information of OAC1, the solubility of OAC1 in water, the solubility of OAC1 in DMSO, the solubility of OAC1 in PBS buffer, the animal experiment (test) of OAC1, the cell expriment (test) of OAC1, the in vivo, in vitro and clinical trial test of OAC1, the EC50, IC50,and affinity,of OAC1, For the detailed information of OAC1, the solubility of OAC1 in water, the solubility of OAC1 in DMSO, the solubility of OAC1 in PBS buffer, the animal experiment (test) of OAC1, the cell expriment (test) of OAC1, the in vivo, in vitro and clinical trial test of OAC1, the EC50, IC50,and affinity,of OAC1, Please contact DC Chemicals.
