Necrostatin-1 产品说明书 Chemicals
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产品编号 DC2084
名称 Necrostatin-1

化学性质

CAS 4311-88-0
分子式 C13H13N3OS
分子量 259.33
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Necrostatin-1 is an inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade. For the detailed information about the solubility of Necrostatin-1 in water, the solubility of Necrostatin-1 in DMSO, the solubility of Necrostatin-1 in PBS buffer, the animal experiment(test) of Necrostatin-1,the in vivo,in vitro and clinical trial test of Necrostatin-1,the cell experiment(test) of Necrostatin-1,the IC50, EC50 and Affinity of Necrostatin-1, please contact DC Chemicals.
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