2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Necrostatin-1 is an inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.
For the detailed information about the solubility of Necrostatin-1 in water, the solubility of Necrostatin-1 in DMSO, the solubility of Necrostatin-1 in PBS buffer, the animal experiment（test） of Necrostatin-1,the in vivo,in vitro and clinical trial test of Necrostatin-1,the cell experiment（test） of Necrostatin-1,the IC50, EC50 and Affinity of Necrostatin-1, please contact DC Chemicals.
