Pazopanib 产品说明书 Chemicals
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产品编号 DC2600
名称 Pazopanib

化学性质

CAS 444731-52-6
分子式 C21H23N7O2S
分子量 437.52
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Pazopanib hydrochloride is an approved drug, is the hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). For the detailed information about the solubility of Pazopanib in water, the solubility of Pazopanib in DMSO, the solubility of Pazopanib in PBS buffer, the animal experiment(test) of Pazopanib,the in vivo,in vitro and clinical trial test of Pazopanib,the cell experiment(test) of Pazopanib,the IC50, EC50 and Affinity of Pazopanib, please contact DC Chemicals.
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