Sorafenib (BAY-43-9006) 产品说明书 Chemicals
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产品编号 DC2098
名称 Sorafenib (BAY-43-9006)

化学性质

CAS 475207-59-1
分子式 C21H16CLF3N4O3.C7H8O3S
分子量 637.03
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Sorafenib tosylate is the tosylate salt of sorafenib, a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). For the detailed information about the solubility of Sorafenib (BAY-43-9006) in water, the solubility of Sorafenib (BAY-43-9006) in DMSO, the solubility of Sorafenib (BAY-43-9006) in PBS buffer, the animal experiment(test) of Sorafenib (BAY-43-9006),the in vivo,in vitro and clinical trial test of Sorafenib (BAY-43-9006),the cell experiment(test) of Sorafenib (BAY-43-9006),the IC50, EC50 and Affinity of Sorafenib (BAY-43-9006), please contact DC Chemicals.
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