2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Natural acacetin was a 4.0-fold and 5.5-fold more potent inhibitor of BACE-1 than oleanolic acid and maslinic acid, respectively.
Acacetin significantly suppressed the photoreceptor collapse.
Acacetin significantly reduces the Aβ levels by interfering with human APP proteolytic processing and BACE-1 expression.
Acacetin inhibited the generation of the APP-CTF by affecting APP cleavage.
Acacetin prolongs lifespan of significantly in the dose dependent manner. Acacetin
(25 uM) had the greatest effect on longevity, extending mean lifespan significantly by 27.31% at 25 uM concentration
