SNAP-94847 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 1.69 nM; displays an anxiolytic/antidepressant-like effect in mouse models, stimulates the proliferation of progenitors in the dentate gyrus; has a unique anxiolytic-like profile that is distinct from selective serotonin reuptake inhibitors and tricyclic antidepressants.ObesityDiscontinued