Naloxone HCl Dihydrate 产品说明书 Chemicals
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产品编号 DC8407
名称 Naloxone HCl Dihydrate

化学性质

CAS 51481-60-8
分子式 C19H26CLNO6
分子量 399.87
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


The Ki values of (−)-naloxone for the MOR, KOR, and DOR are 0.559 nM, 4.91 nM, and 36.5 nM, respectively. Naloxone HCl Dihydrate binds to the MOR with approximately 9-fold greater affinity relative to the KOR and around 60-fold greater affinity relative to the DOR.The combination of Naloxone HCl Dihydrate (0.5 mg/kg, i.p.) with tramadol (22 mg/kg) decreases the antiallodynic effect of tramadol. For the detailed information of Naloxone HCl Dihydrate, the solubility of Naloxone HCl Dihydrate in water, the solubility of Naloxone HCl Dihydrate in DMSO, the solubility of Naloxone HCl Dihydrate in PBS buffer, the animal experiment (test) of Naloxone HCl Dihydrate, the cell expriment (test) of Naloxone HCl Dihydrate, the in vivo, in vitro and clinical trial test of Naloxone HCl Dihydrate, the EC50, IC50,and affinity,of Naloxone HCl Dihydrate, For the detailed information of Naloxone HCl Dihydrate, the solubility of Naloxone HCl Dihydrate in water, the solubility of Naloxone HCl Dihydrate in DMSO, the solubility of Naloxone HCl Dihydrate in PBS buffer, the animal experiment (test) of Naloxone HCl Dihydrate, the cell expriment (test) of Naloxone HCl Dihydrate, the in vivo, in vitro and clinical trial test of Naloxone HCl Dihydrate, the EC50, IC50,and affinity,of Naloxone HCl Dihydrate, Please contact DC Chemicals.
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