2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO.It potently inhibits GSK3α/β (IC50 = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC50s = 2.4, 4.3, and 63 µM, respectively).BIO-Acetoxime has been used to study the role of GSK3 in the Wnt/β-catenin pathway.3 It also suppresses the cytopathic effects of herpes viruses and reduces viral yields in human oral epithelial cells. For the detailed information of BIO-Acetoxime, the solubility of BIO-Acetoxime in water, the solubility of BIO-Acetoxime in DMSO, the solubility of BIO-Acetoxime in PBS buffer, the animal experiment (test) of BIO-Acetoxime, the cell expriment (test) of BIO-Acetoxime, the in vivo, in vitro and clinical trial test of BIO-Acetoxime, the EC50, IC50,and affinity,of BIO-Acetoxime, For the detailed information of BIO-Acetoxime, the solubility of BIO-Acetoxime in water, the solubility of BIO-Acetoxime in DMSO, the solubility of BIO-Acetoxime in PBS buffer, the animal experiment (test) of BIO-Acetoxime, the cell expriment (test) of BIO-Acetoxime, the in vivo, in vitro and clinical trial test of BIO-Acetoxime, the EC50, IC50,and affinity,of BIO-Acetoxime, Please contact DC Chemicals.
