BIO-acetoxime 产品说明书 Chemicals
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产品编号 DC8368
名称 BIO-acetoxime

化学性质

CAS 667463-85-6
分子式 C18H12BRN3O3
分子量 398.21
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO.It potently inhibits GSK3α/β (IC50 = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC50s = 2.4, 4.3, and 63 µM, respectively).BIO-Acetoxime has been used to study the role of GSK3 in the Wnt/β-catenin pathway.3 It also suppresses the cytopathic effects of herpes viruses and reduces viral yields in human oral epithelial cells. For the detailed information of BIO-Acetoxime, the solubility of BIO-Acetoxime in water, the solubility of BIO-Acetoxime in DMSO, the solubility of BIO-Acetoxime in PBS buffer, the animal experiment (test) of BIO-Acetoxime, the cell expriment (test) of BIO-Acetoxime, the in vivo, in vitro and clinical trial test of BIO-Acetoxime, the EC50, IC50,and affinity,of BIO-Acetoxime, For the detailed information of BIO-Acetoxime, the solubility of BIO-Acetoxime in water, the solubility of BIO-Acetoxime in DMSO, the solubility of BIO-Acetoxime in PBS buffer, the animal experiment (test) of BIO-Acetoxime, the cell expriment (test) of BIO-Acetoxime, the in vivo, in vitro and clinical trial test of BIO-Acetoxime, the EC50, IC50,and affinity,of BIO-Acetoxime, Please contact DC Chemicals.
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