STF-31 产品说明书 Chemicals
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产品编号 DC8359
名称 STF-31

化学性质

CAS 724741-75-7
分子式 C23H25N3O3S
分子量 423.5
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


STF-31 is an inhibitor of GLUT1 (IC50 = ~1 µM) that blocks glucose uptake.It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress GLUT1.Although STF-31 binds GLUT1, suggesting a direct effect, STF-31 also inhibits nicotinamide phosphoribosyltransferase, an enzyme that induces GLUT1 expression. STF-31 is also toxic to human pluripotent stem cells (hPSCs) and can be used to selectively eliminate hPSCs from mixed cultures. For the detailed information of STF-31, the solubility of STF-31 in water, the solubility of STF-31 in DMSO, the solubility of STF-31 in PBS buffer, the animal experiment (test) of STF-31, the cell expriment (test) of STF-31, the in vivo, in vitro and clinical trial test of STF-31, the EC50, IC50,and affinity,of STF-31, For the detailed information of STF-31, the solubility of STF-31 in water, the solubility of STF-31 in DMSO, the solubility of STF-31 in PBS buffer, the animal experiment (test) of STF-31, the cell expriment (test) of STF-31, the in vivo, in vitro and clinical trial test of STF-31, the EC50, IC50,and affinity,of STF-31, Please contact DC Chemicals.
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