化学性质
CAS |
736992-21-5 |
 |
分子式 |
C34H60F3N9O7 |
分子量 |
753.81 |
存储条件 |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
生物活性
Description |
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In Vivo |
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In Vitro |
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化合物的使用
Kinase Assay |
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Cell Assay |
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Animal Administration |
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参考文献
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types; prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function.
Other Indication
Phase 3 Clinical |
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