PTC124 (Ataluren) 产品说明书 Chemicals
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产品编号 DC2005
名称 PTC124 (Ataluren)

化学性质

CAS 775304-57-9
分子式 C15H9FN2O3
分子量 284.24
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Description of Ataluren: Ataluren (PTC124) is an investigational new drug designed to enable the Formation of a functioning protein in patients with genetic disorders due to a nonsense mutation. A nonsense mutation is an alteration in the genetic code that prematurely halts the synthesis of an essential protein. Ataluren is currently being investigated For use in patients with nonsense mutation Duchenne/Becker muscular dystrophy (nmDBMD) and cystic fibrosis (nmCF) (source: http://www.ptcbio.com/ataluren). For the detailed information about the solubility of PTC124 (Ataluren) in water, the solubility of PTC124 (Ataluren) in DMSO, the solubility of PTC124 (Ataluren) in PBS buffer, the animal experiment(test) of PTC124 (Ataluren),the in vivo,in vitro and clinical trial test of PTC124 (Ataluren),the cell experiment(test) of PTC124 (Ataluren),the IC50, EC50 and Affinity of PTC124 (Ataluren), please contact DC Chemicals.
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