GNF-2 产品说明书 Chemicals
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产品编号 DC1062
名称 GNF-2

化学性质

CAS 778270-11-4
分子式 C18H13F3N4O2
分子量 374.32
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Description of GNF-2: GNF-2 is an allosteric inhibitor of Bcr-abl tyrosine kinase activity (IC50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells. Selective For Bcr-abl over a panel of serine, threonine and tyrosine kinases. Non-ATP-competitive. For the detailed information about the solubility of GNF-2 in water, the solubility of GNF-2 in DMSO, the solubility of GNF-2 in PBS buffer, the animal experiment(test) of GNF-2,the in vivo,in vitro and clinical trial test of GNF-2,the cell experiment(test) of GNF-2,the IC50, EC50 and Affinity of GNF-2, please contact DC Chemicals.
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