2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
A potent and selective GC-C agonist (Ki=1.23-1.64 nM) that elicits pharmacological effects locally in the gastrointestinal tract; induces a significant increase in fluid secretion, accompanied by a significant increase in intraluminal cGMP levels; has potential for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.Irritable Bowel SyndromeApproved
