Ripasudil(K-115) 产品说明书 Chemicals
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产品编号 DC7774
名称 Ripasudil(K-115)

化学性质

CAS 887375-67-9
分子式 C15H23CLFN3O4S
分子量 395.88
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


K-115, an isoquinolinesulfonamide compound, is a highly selective and potent (IC50 = 31 nM) Rho-kinase inhibitor; is in Phase II clinical development in patients with POAG or ocular hypertension. IC50 value: 31 nM Target: ROCK inhibitor K-115 had selecti
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