2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. This compound has some degree of selectivity over quite a few kinases with the exceptions of CHK1, CK2, and PLK. Although compound 2b(DB-07268) shows submicromolar potency against these three kinases, it still appears to exhibit at least 70- to 90-fold greater potency against JNK1 than CHK1, CK2, and PLK.
