PF 429242 产品说明书 Chemicals
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产品编号 DC8059
名称 PF 429242

化学性质

CAS 947303-87-9
分子式 C25H35N3O2.2HCL
分子量 482.49
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV. For the detailed information of PF 429242, the solubility of PF 429242 in water, the solubility of PF 429242 in DMSO, the solubility of PF 429242 in PBS buffer, the animal experiment (test) of PF 429242, the cell expriment (test) of PF 429242, the in vivo, in vitro and clinical trial test of PF 429242, the EC50, IC50,and affinity,of PF 429242, For the detailed information of PF 429242, the solubility of PF 429242 in water, the solubility of PF 429242 in DMSO, the solubility of PF 429242 in PBS buffer, the animal experiment (test) of PF 429242, the cell expriment (test) of PF 429242, the in vivo, in vitro and clinical trial test of PF 429242, the EC50, IC50,and affinity,of PF 429242, Please contact DC Chemicals.
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