Pyridostatin trifluoroacetate salt

产品编号: DC8091 Featured
Pyridostatin trifluoroacetate salt
结构式
1085412-37-8
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中国地区超过5000个高品质化合物库存
应用领域
Pyridostatin 是一种 G-quadruplexe 稳定剂,Kd 值为 490 nM。
Cas No.: 1085412-37-8
名称: 4-(2-Aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinedicarboxamide
别名: RR82,RR-82
SMILES: C(C(NC1C=C(OCCN)C2C(N=1)=CC=CC=2)=O)1=NC(C(NC2C=C(OCCN)C3C(N=2)=CC=CC=3)=O)=CC(OCCN)=C1.C(O)(=O)C(F)(F)F
分子式: C31H32N8O5.XC2Hf3O2
分子量: 596.63(free base)
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Pyridostatin(RR 82) binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs). For the detailed information of Pyridostatin trifluoroacetate salt, the solubility of Pyridostatin trifluoroacetate salt in water, the solubility of Pyridostatin trifluoroacetate salt in DMSO, the solubility of Pyridostatin trifluoroacetate salt in PBS buffer, the animal experiment (test) of Pyridostatin trifluoroacetate salt, the cell expriment (test) of Pyridostatin trifluoroacetate salt, the in vivo, in vitro and clinical trial test of Pyridostatin trifluoroacetate salt, the EC50, IC50,and affinity,of Pyridostatin trifluoroacetate salt, For the detailed information of Pyridostatin trifluoroacetate salt, the solubility of Pyridostatin trifluoroacetate salt in water, the solubility of Pyridostatin trifluoroacetate salt in DMSO, the solubility of Pyridostatin trifluoroacetate salt in PBS buffer, the animal experiment (test) of Pyridostatin trifluoroacetate salt, the cell expriment (test) of Pyridostatin trifluoroacetate salt, the in vivo, in vitro and clinical trial test of Pyridostatin trifluoroacetate salt, the EC50, IC50,and affinity,of Pyridostatin trifluoroacetate salt, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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