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Pyridostatin(RR 82) binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs). For the detailed information of Pyridostatin trifluoroacetate salt, the solubility of Pyridostatin trifluoroacetate salt in water, the solubility of Pyridostatin trifluoroacetate salt in DMSO, the solubility of Pyridostatin trifluoroacetate salt in PBS buffer, the animal experiment (test) of Pyridostatin trifluoroacetate salt, the cell expriment (test) of Pyridostatin trifluoroacetate salt, the in vivo, in vitro and clinical trial test of Pyridostatin trifluoroacetate salt, the EC50, IC50,and affinity,of Pyridostatin trifluoroacetate salt, For the detailed information of Pyridostatin trifluoroacetate salt, the solubility of Pyridostatin trifluoroacetate salt in water, the solubility of Pyridostatin trifluoroacetate salt in DMSO, the solubility of Pyridostatin trifluoroacetate salt in PBS buffer, the animal experiment (test) of Pyridostatin trifluoroacetate salt, the cell expriment (test) of Pyridostatin trifluoroacetate salt, the in vivo, in vitro and clinical trial test of Pyridostatin trifluoroacetate salt, the EC50, IC50,and affinity,of Pyridostatin trifluoroacetate salt, Please contact DC Chemicals. |