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生物活性小分子
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RAD51
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Wee1
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Arp2/3 complex
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MicroRNA
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GPCR
5-HT Receptor
Adenosine Receptor
Adrenergic Receptor
Angiotensin Receptor
Bombesin Receptor
Bradykinin Receptor
Calcium-sensing Receptor (CaSR)
Cannabinoid Receptor
CGRP Receptor
Chemokine Receptor (CCR and CXCR)
Cholecystokinin Receptor
CRF Receptor
Dopamine Receptor
Endothelin Receptor
Free Fatty Acid Receptor (FFAR)
Galanin Receptor
Ghrelin Receptor (GHSR)
Glucagon Receptor
GNRH Receptor
GPCR19 (TGR5)
GPER (GPR30)
GPR109A (Niacin Receptor 1)
GPR119
GPR139
GPR183 (EBI2)
GPR39
GPR55
GPR84
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mAChR
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Melanocortin Receptor
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mGluR
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Opioid Receptor
Orexin Receptor
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P2Y Receptor
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Protease-activated Receptor (PAR)
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PTH Receptor
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IRAK
MyD88
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PD-1/PD-L1
PGE synthase
RIG-I-like Receptor (RLR)
Scavenger Receptor
Sphingosine kinase (SphK)
STING
T Cell Receptor (TCR)
Thrombopoietin Receptor (CD110)
Toll-like Receptor (TLR)
JAK/STAT Signaling
JAK
Pim
STAT
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Exportin-1 (CRM1,XPO1)
FABP
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iGluR
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nAChR
Na-K-ATPase
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P2X Receptor
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SGLT
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URAT1
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11β-HSD
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Adenylate Cyclase
Aldehyde Dehydrogenase (ALDH)
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Dopamine beta-hydroxylase
Elastase
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FAAH
Factor Xa
Farnesyl transferase (FTase)
Fatty Acid Synthase
Fumarase
Glucokinase
Glycogen Synthase
Guanylate Cyclase
Gutathione S-transferase (GST)
Hexokinase
HMG-CoA Reductase (HMGCR)
IMPDH
Indoleamine 2,3-Dioxygenase (IDO)
Isocitrate Dehydrogenase (IDH)
Kynurenine 3-Monooxygenase (KMO)
Lactate Dehydrogenase (LDH)
Lipoxygenase
Matrix Metalloproteinase (MMP)
Monoacylglycerol Lipase (MAGL)
Monoamine Oxidase (MAO)
NADPH Oxidase (NOX)
NAMPT
Neprilysin
Phosphodiesterase (PDE)
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Protein Arginine Deiminase (PAD)
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Renin
SGK
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Stearoyl-CoA Desaturase (SCD)
Steroid Sulfatase (STS)
Thrombin
Tryptophan Hydroxylase (TPH)
Xanthine Oxidase (XAO)
NF-κB Pathway
IκB kinase (IKK)
MALT1
NF-κB
NF-κB inducing Kinase (NIK)
TAK1
Nuclear Receptor/Transcription Factor
Androgen Receptor (AR)
Aryl hydrocarbon Receptor (AhR)
c-Fos/AP-1
c-Myc
CREB/CBP
Estrogen Receptor/ERR
Eukaryotic Initiation Factor (eIF)
Farnesoid X Receptor (FXR)
Foxo1
GATA Binding Protein
Glucocorticoid receptor (GR)
HIF/HIF Prolyl-hydroxylase
IRE1
Keap1-Nrf2
Kruppel-like Factor (KLF)
Liver X Receptor (LXR)
Mineralocorticoid Receptor (MLR)
MITF
Nur77 (NR4A1)
NURR1 (NR4A2)
Oct3/4
PGC-1α
PPAR
Pregnane X Receptor (PXR)
Progesterone Receptor
RAR/RXR
Rev-ErbA
ROR
RUNX1-CBFβ
Thyroid Hormone Receptor (THR)
Vitamin D Receptor (VDR)
Yes-associated Protein (YAP)
Others
14-3-3 Protein
Amyloids
AP2-associated Kinase 1 (AAK1)
CaMK
CETP
Choline Kinase (ChoK)
Clathrin
Diacylglycerol Kinase (DGK)
Fluorescent Dye
GRK (GPCRK)
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Other Targets
PCSK9
SMN2 Modulator
Spliceosome
Translocator Protein (TSPO)
PI3K/Akt/mTOR
Akt
AMPK
MELK
mTOR
PDK1
PI3K
PI4K
PIKfyve
PTEN
Proteasome/Ubiquitin
Deubiquitinase (DUB)
E3 Ubiquitin Ligase
Heat Shock Protein (HSP)
NEDD8
p97/VCP
Proteasome
Ubiquitin-activating Enzyme (E1)
Ubiquitin-conjugating Enzyme (E2)
Ras-Raf-MAPK-ERK
ERK
JNK
MAP4K
MAPKAPK2 (MK2)
MEK (MAP2K)
MEKK (MAP3K)
Mixed Lineage Kinase (MLK)
MNK
p38 MAPK
Protein Kinase A (PKA)
Raf
Ras
Ribosomal S6 Kinase (RSK)
TOPK
TGF-beta/Smad
PKC
TGF beta Receptor (TGFBR)
Tyrosine Kinase
Ack1 (TNK2)
Anaplastic Lymphoma Kinase (ALK)
Angiopoietin Receptor
Bcr-Abl
BMX Kinase
Breast Tumor Kinase (BRK;PTK6)
BTK
c-Fes Kinase
c-Fms (CSF1R)
c-Kit
c-Met (HGFR)
Discoidin Domain Receptor (DDR)
DYRK
EGFR
Ephrin Receptor
FGFR
FLT3
Focal Adhesion Kinase (FAK)
IGF-1R
Insulin Receptor
ITK
PDGFR
RET Tyrosine Kinase (c-RET)
Src
Syk
TAM Receptor (Tyro3-Axl-Mer)
Tec Kinase
Trk Receptor
VEGFR
Wnt/Notch/Hedgehog
Autotaxin
Axin
Beta-catenin
BMI-1
Casein Kinase
Dickkopf-1 (Dkk-1)
Dishevelled
Frizzled
Gli
GSK-3
Hedgehog (Hh)
Hippo
Notch
Smoothened (Smo)
TNIK
Wnt
γ-secretase
研究领域
Cancer
Blood Cancer
Bone Cancer
Brain Cancer
Breast Cancer
Chemotherapeutic Agents
Colon Cancer
Gastric Cancer
Kidney Cancer
Liver Cancer
Lung Cancer
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer
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Solid Tumors
Thyroid Cancer
Infection
Bacterial Infection
CMV Infection
Ebola Virus Infection
Fungal Infection
HBV Infection
HCV Infection
HIV Infection
HPV Infection
HSV Infection
Influenza
Parasite Infection
Rhinovirus Infection
RSV Infection
SARS-CoV Infection
Endocrine Disorders
Cushing Disease
Growth Hormone Deficiency
Hyperparathyroidism
Sexual Dysfunction
Cardiovascular Disease
Atherosclerosis
Coagulation Disorder
Dyslipidemia
Heart Arrhythmia
Heart Failure
Hypercholesterolemia
Hypertension
Ischemia
Thrombosis
Inflammation/Autoimmune Disease
Allergy
Asthma
COPD
Dermatitis
Gout
Multiple Sclerosis
Psoriasis
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Metabolic Disorder
Diabetes
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Alcoholism
Alzheimer Disease
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Depression
Epilepsy
Migraine
Pain
Parkinson Disease
Schizophrenia
Sleep Disorder
Spinal Muscular Atrophy (SMA)
Stroke
Other Indications
Anemia
Fibrosis
Irritable Bowel Syndrome
Other Indication
Steatohepatitis
Ulcer
Cationic Lipid
PROTACs化合物
E3 Ligase Ligand
E3 Ligase Ligand-Linker Conjugate
PEGn
PROTAC
Antibody Drug Conjugates
ADC Cytotoxin
ADCs Linker/Click Chemistry
Drug-Linker Conjugates
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Choline Kinase (ChoK)
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CAS No.
1026657369
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