首页 > 生物活性小分子 > Cell Cycle/DNA Damage > DNA Alkylator/Crosslinker
产品编号 产品名称 CAS No.
DC10611 Trabectedin

Trabectedin (Ecteinascidin-743 or ET-743)是海洋来源的抗癌剂。

114899-77-3
DC2099 Cisplatin

Cisplatin (CDDP) 是一种抗肿瘤的化疗剂,它与 DNA 交联引起癌细胞中 DNA 损伤。Cisplatin 可激活铁死亡 (ferroptosis) 并诱导自噬 (autophagy)。

15663-27-1
DC7689 Evofosfamide(TH-302)

Evofosfamide (TH-302) 是一种缺氧 (hypoxia) 激活前药,缺氧 (N2) 和常氧 (21% O2) 环境下,IC50 分别为 10 μM 和 1000 μM。

918633-87-1
DC4182 Temozolomide

Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.

85622-93-1
DC8935 Mitomycin C

Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells.

50-07-7
DC9013 Cyclophosphamide

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

50-18-0
DC9095 Carboplatin

Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism.

41575-94-4
DC9298 thiotepa

N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.

52-24-4
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