Trabectedin (Ecteinascidin-743 or ET-743)是海洋来源的抗癌剂。

Cisplatin (CDDP) 是一种抗肿瘤的化疗剂，它与 DNA 交联引起癌细胞中 DNA 损伤。Cisplatin 可激活铁死亡 (ferroptosis) 并诱导自噬 (autophagy)。

Evofosfamide (TH-302) 是一种缺氧 (hypoxia) 激活前药，缺氧 (N2) 和常氧 (21% O2) 环境下，IC50 分别为 10 μM 和 1000 μM。

Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.

Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism.

N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.