VU0361737(ML128)

产品编号: DC7339 Featured
VU0361737(ML128)
结构式
1161205-04-4
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中国地区超过5000个高品质化合物库存
应用领域
VU 0361737是一种选择性mGlu4受体正变构调节剂 (PAM),作用于人类和大鼠受体, EC50分别为240 nM和110 nM, 对mGlu5和mGlu8受体具有微弱的作用活性, 对 mGlu1,mGlu2,mGlu3,mGlu6 和mGlu7受体没有抑制活性。
Cas No.: 1161205-04-4
名称:
别名: ML-128; VU-0361737; VU 0361737,ML128,ML 128
SMILES: COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl
分子式: C13H11ClN2O2
分子量: 262.69
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: VU0361737 is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors.For the detailed information of VU 0361737, the solubility of VU 0361737 in water, the solubility of VU 0361737 in DMSO, the so
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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