PS48

产品编号: DC22313 Featured
PS48
结构式
1180676-32-7
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中国地区超过5000个高品质化合物库存
应用领域
PS48 是 一种 PDK1 激活剂,AC50 为 8 μM。
Cas No.: 1180676-32-7
名称: 5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid
别名: PS-48,PS 48,PS48
SMILES: C1=CC=C(C=C1)/C(=C\C(=O)O)/CCC2=CC=C(C=C2)Cl
分子式: C17H15ClO2
分子量: 286.75
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_1135_DC22313_1180676-32-7
COA
LOT NO. DOWNLOAD
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