PF 3845

产品编号: DC7611 Featured
PF 3845
结构式
1196109-52-0
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中国地区超过5000个高品质化合物库存
应用领域
PF-3845 是选择性脂肪酰胺水解酶(FAAH)抑制剂,Ki为230nM,对FAAH2几乎无活性。
Cas No.: 1196109-52-0
名称: N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide
别名: PF3845, PF3845
SMILES: C1CN(CCC1CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=CN=CC=C4
分子式: C24H23F3N4O2
分子量: 456.46
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM).It covalently binds FAAH on Ser241 at the catalytic site, resulting in prolonged elevation of AEA in the brain and plasma in rats after treatment.PF-3845 significantly and p
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_1851_DC7611_1196109-52-0
COA
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