| References: |
UNC0224 is a potent and selective G9a HMTase inhibitor, exhibiting an IC50 value of 15 nM.Isothermal titration calorimetry revealed UNC0224 binds to G9a with a Kd value of 29 nM. UNC0224 also inhibits GLP, a closely-related H3K9 HMTase, with assay-dependent IC50 values of 20-58 nM, but is more than 1,000-fold selective against SET7/9 (a H3K4 HMTase) and SET8 (a H4K20 HMTase). For the detailed information of UNC-0224, the solubility of UNC-0224 in water, the solubility of UNC-0224 in DMSO, the solubility of UNC-0224 in PBS buffer, the animal experiment (test) of UNC-0224, the cell expriment (test) of UNC-0224, the in vivo, in vitro and clinical trial test of UNC-0224, the EC50, IC50,and affinity,of UNC-0224, For the detailed information of UNC-0224, the solubility of UNC-0224 in water, the solubility of UNC-0224 in DMSO, the solubility of UNC-0224 in PBS buffer, the animal experiment (test) of UNC-0224, the cell expriment (test) of UNC-0224, the in vivo, in vitro and clinical trial test of UNC-0224, the EC50, IC50,and affinity,of UNC-0224, Please contact DC Chemicals. |
