Trilostane(Win 24540; Modrastane)

产品编号: DC8629 Featured
Trilostane(Win 24540; Modrastane)
结构式
13647-35-3
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中国地区超过5000个高品质化合物库存
应用领域
Trilostane(Win 24540; Modrastane)是3 β-羟化类固醇脱氢酶抑制剂,可作用于库兴氏综合征。
Cas No.: 13647-35-3
名称:
别名: Modrastane; Modrefen; Modrenal; Vetoryl; Win 24540
SMILES: C(O)1[C@@]([H])2O[C@]22[C@@](C)(CC=1C#N)[C@]([H])1[C@@]([H])([C@@]([H])3[C@](CC1)(C)[C@H](O)CC3)CC2
分子式: C20H27NO3
分子量: 329.43
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Trilostane(Win 24540; Modrastane) is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase (3-β-HSD or delta 5-delta 4-isomerase), an essential enzyme for the biosynthesis of all classes of hormonal steroids. It has been used in the treatment of Cushing′s syndrome for stopping the production of cortisol, and is currently approved for dogs in the US, but is still a human drug in the UK and other countries. It is being investigated as a possible treatment for both breast cancer and prostate cancer to prevent the synthesis of estrogens and androgens from endogenous precursors. It has also been used to inhibit endogenous production of progesterone in research studies.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_2435_DC8629_13647-35-3
COA
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