UU-T02|1500080-17-0|Other Targets Inhibitors & Agonists|DC Chemicals

Cas No.:	1500080-17-0
名称:	(S)-4-((S)-3-carboxy-2-((S)-2-(2-(5-chloro-1H-indol-2-yl)acetamido)-3-(naphthalen-2-yl)propanamido)propanamido)-5-methoxy-5-oxopentanoic acid
别名:	UU-T02; UU-T-02; UU-T 02; UUT02; UUT-02; UUT 02
SMILES:	O=C(O)CC[C@H](NC([C@@H](NC([C@@H](NC(CC(N1)=CC2=C1C=CC(Cl)=C2)=O)CC3=CC=C4C=CC=CC4=C3)=O)CC(O)=O)=O)C(OC)=O
分子式:	C₃₃H₃₃ClN₄O₉
分子量:	665.096
纯度:
保存条件:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:
In Vivo:
In Vitro:
References:	UU-T02 is a potent, selective small-molecule inhibitor of β-catenin/Tcf4 interaction. The β-catenin/T-cell factor (Tcf) protein−protein interaction (PPI) plays a critical role in the β-catenin signaling pathway which is hyperactivated in many cancers and fibroses. UU-T02 disrupted β-catenin/Tcf PPI with a Ki of 1.36 μM in the fluorescence polarization (FP) competitive inhibition assay and displayed 175- and 64-fold selectivity over β-catenin/E-cadherin and β-catenin/APC, respectively. 东苍生物联系我们关于我们总部经销商服务项目定制合成工艺研发知识产权保护外包客户支持技术支持订购信息轻松退货运费政策资源和工具免费样品文献稀释换算摩尔浓度换算动物实验计量标准细则条款免费咨询电话：4008862077 QQ：1026657369 邮箱：order@dcbio.cn 我们所有的产品仅供研究所需，严禁用于人体和其他目的站点地图\|隐私政策Copyright © 2018-2020 All Rights Reserved. 技术支持:库价软件 1026657369 order@dcbio.cn 13585906077

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