KB-R7943 mesylate

产品编号: DC7832 Featured
KB-R7943  mesylate
结构式
182004-65-5
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中国地区超过5000个高品质化合物库存
应用领域
KB-R7943 mesylate 是一种 Na+/Ca2+ 交换体 (NCXrev) 反向抑制剂,IC50 为 5.7±2.1 µM。KB-R7943 mesylate 通过激活JNK通路和抑制自噬通量来诱导癌细胞死亡.
Cas No.: 182004-65-5
名称: methanesulfonic acid;2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate
别名: KB R7943; KB-R 7943, KBR7943, 182004-65-5, KB-R7943 mesylate, 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE, IN1281, KB-R 7943
SMILES: N=C(N)SCCC1=CC=C(OCC2=CC=C([N+]([O-])=O)C=C2)C=C1.OS(C)(=O)=O
分子式: C17H21N3O6S2
分子量: 427.49514
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: KB-R7943 mesylate is a cell permeable, potent, selective NCKX inhibitor of the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1. NCX1 is a Na+/Ca2+ exchanger predominantly expressed in cardiac sarcolemma, as well as in brain, kidney, liver, panc
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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