S-Gboxin

产品编号: DC22332 Featured
S-Gboxin
结构式
2101317-21-7
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中国地区超过5000个高品质化合物库存
应用领域
S-Gboxin 是 Gboxin 的功能类似物,S-Gboxin 抑制小鼠和人胶质母细胞瘤的生长,IC50 为 470 nM。具有抗肿瘤活性。
Cas No.: 2101317-21-7
名称:
别名:
SMILES: FC(C1=CC(C2=[N+](CC(O[C@H]3[C@H](C(C)C)CC[C@@H](C)C3)=O)C4=CC=CC=C4N2C)=CC=C1)(F)F.[I-]
分子式: C27H32F3In2O2
分子量: 600.4647
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits growth of mouse and human glioblastoma (GBM) with an IC50 of 470 nM. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Gboxin inhibits the growth of primary mouse and human glioblastoma cells but not that of mouse embryonic fibroblasts or neonatal astrocytes. Gboxin rapidly and irreversibly compromises oxygen consumption in glioblastoma cells.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_1149_DC22332_2101317-21-7
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