BAY2335218(BAY-218)

产品编号: DC26020 Featured
BAY2335218(BAY-218)
结构式
2162982-11-6
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中国地区超过5000个高品质化合物库存
应用领域
AHR antagonist 1 是一种芳基烃受体 (AHR) 拮抗剂,在人细胞系中的 IC50 值为 39.9 nM,详细信息请参考 WO2017202816A1,Example 23。
Cas No.: 2162982-11-6
名称: (S)-6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide
别名: BAY2335218,BAY-2335218,BAY 2335218,BAY218,BAY 218,BAY-218
SMILES: O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CC=CC(F)=C3)C1=O)N[C@@H](C)CO
分子式: C20H17ClFN3O3
分子量: 401.82
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: BAY2335218(BAY-218) showed IC50 values for human and murine AhR 45 and 43 nM, respectively, IC50 values of 76 and 66 for human and murine CYP1A1 mRNA in cellular functional assays, respectively.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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