MPEP hydrochloride

产品编号: DC8339 Featured
MPEP hydrochloride
结构式
219911-35-0
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中国地区超过5000个高品质化合物库存
应用领域
MPEP盐酸盐是非竞争性mGlu5受体拮抗剂,IC50为36 nM。
Cas No.: 219911-35-0
名称: 2-Methyl-6-(phenylethynyl)pyridine hydrochloride
别名:
SMILES: C(C)1=NC(C#CC2=CC=CC=C2)=CC=C1.[H]Cl
分子式: C14H11N.HCl
分子量: 229.71
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. For the detailed information of MPEP hydrochloride, the solubility of MPEP hydrochloride in water, the solubility of MPEP hydrochloride in DMSO, the solubility of MPEP hydrochloride in PBS buffer, the animal experiment (test) of MPEP hydrochloride, the cell expriment (test) of MPEP hydrochloride, the in vivo, in vitro and clinical trial test of MPEP hydrochloride, the EC50, IC50,and affinity,of MPEP hydrochloride, For the detailed information of MPEP hydrochloride, the solubility of MPEP hydrochloride in water, the solubility of MPEP hydrochloride in DMSO, the solubility of MPEP hydrochloride in PBS buffer, the animal experiment (test) of MPEP hydrochloride, the cell expriment (test) of MPEP hydrochloride, the in vivo, in vitro and clinical trial test of MPEP hydrochloride, the EC50, IC50,and affinity,of MPEP hydrochloride, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_2286_DC8339_219911-35-0
COA
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