| References: |
RBC8 or BQU57 treatment showed no further inhibition of colony formation after Ral knockdown. RBC8 and BQU57 showed favorable properties that define good drug candidates. To test the effect of Ral inhibitors on xenograft tumor growth, nude mice were inoculated subcutaneously with H2122 human lung cancer cells and treated intraperitoneally with 50 mg/kg/d of RBC8 for 21 days (except weekends). RBC8 inhibited tumor growth to a similar extent as dual knockdown of RalA and RalB. For the detailed information of RBC8, the solubility of RBC8 in water, the solubility of RBC8 in DMSO, the solubility of RBC8 in PBS buffer, the animal experiment (test) of RBC8, the cell expriment (test) of RBC8, the in vivo, in vitro and clinical trial test of RBC8, the EC50, IC50,and affinity,of RBC8, For the detailed information of RBC8, the solubility of RBC8 in water, the solubility of RBC8 in DMSO, the solubility of RBC8 in PBS buffer, the animal experiment (test) of RBC8, the cell expriment (test) of RBC8, the in vivo, in vitro and clinical trial test of RBC8, the EC50, IC50,and affinity,of RBC8, Please contact DC Chemicals. |
