Fluticasone furoate

产品编号: DC10020 Featured
Fluticasone furoate
结构式
397864-44-7
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中国地区超过5000个高品质化合物库存
应用领域
Fluticasone furoate 是一种局部,鼻内,增强亲和力的合成的三氟皮质类固醇,Kd 为 0.3 nM。Fluticasone furoate 具有有效的抗炎和抗哮喘活性,并且全身暴露率低。Fluticasone furoate 可用于过敏性鼻炎的研究。
Cas No.: 397864-44-7
名称:
别名:
SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)SCF)OC(=O)C5=CC=CO5)C)O)F)C)F
分子式: C27H29F3O6S
分子量: 538.57
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Fluticasone furoate is available as a combination product with vilanterol, a long-acting beta-2 agonist, under the tradename Breo Ellipta. Approved by the FDA in 2013, its use is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.
Kinase Assay:
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Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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