CASIN

产品编号: DC8013 Featured
CASIN
结构式
425399-05-9
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中国地区超过5000个高品质化合物库存
应用领域
CASIN是一个选择性的GTPase Cdc42抑制剂,IC50值是2 uM。
Cas No.: 425399-05-9
名称: 2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol
别名:
SMILES: C1=CC=CC=C1C1=CC2C3CCCC(NCCO)C=3NC=2C=C1
分子式: C20H22N2O
分子量: 306.4
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: CASIN is a Cdc42 GTPase inhibitor (IC50 = 2 μM). CASIN reduces active levels of Cdc42 in aged hematopoietic stem cells (HSCs) to that in young HSCs. CASIN reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo.CASIN increases histone H4K16 acetylation in aged HSCs. For the detailed information of CASIN, the solubility of CASIN in water, the solubility of CASIN in DMSO, the solubility of CASIN in PBS buffer, the animal experiment (test) of CASIN, the cell expriment (test) of CASIN, the in vivo, in vitro and clinical trial test of CASIN, the EC50, IC50,and affinity,of CASIN, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_2072_DC8013_425399-05-9
COA
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