Ochratoxin B(OTB)

产品编号: DC10145 Featured
Ochratoxin B(OTB)
结构式
4825-86-9
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中国地区超过5000个高品质化合物库存
应用领域
Ochratoxin B 是 Aspergillus ochraceus 的次级代谢产物,是霉菌毒素 Ochratoxin A 的非氯化类似物。Ochratoxin B 已被证明可降低 Ochratoxin A 的毒性作用,它是啮齿动物中最有效的肾脏致癌物质之一。
Cas No.: 4825-86-9
名称: N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine
别名: OTB
SMILES: C[C@@H]1CC2=C(C=C(C(=C2C(=O)O1)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)
分子式: C20H19NO6
分子量: 369.4
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Ochratoxin B(OTB) is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion.OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 µg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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