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Salinomycin sodium

产品编号: DC22349 Featured
Salinomycin sodium
结构式
55721-31-8
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中国地区超过5000个高品质化合物库存
应用领域
Salinomycin sodium salt (Salinomycin sodium)，一种钾离子载体抗生素，是 Wnt/β-catenin 信号传导的有效抑制剂。Salinomycin sodium salt (Salinomycin sodium) 作用于 Wnt/Fzd/LRP 复合物，阻断 Wnt 诱导的 LRP6 磷酸化，导致 LRP6 蛋白降解。Salinomycin sodium salt (Salinomycin sodium) 选择性抑制人肿瘤干细胞。
化学性质生物活性化合物的使用COA & MSDS相关产品产品说明书
Cas No.: 55721-31-8
名称: Salinomycin, sodium salt (1:1)
别名: Sodium salinomycin
SMILES: [H][C@]1([C@](C)(CC2)O[C@]32[C@H](O)C=C[C@]4(O[C@]([H])([C@@H](CC)C([C@@H](C)[C@@H](O)[C@H](C)[C@]5([H])O[C@]([C@@H](CC)C([O-])=O)([H])CC[C@@H]5C)=O)[C@@H](C)C[C@H]4C)O3)CC[C@@](CC)(O)[C@H](C)O1.[Na+]
分子式: C42H69NaO11
分子量: 772.9804
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: A polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration; inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells; induces ER stress‑mediated autophagy and apoptosis through generation of ROS in human glioma U87MG cells.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_1161_DC22349_55721-31-8
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