Miltefosine

产品编号: DC9120 Featured
Miltefosine
结构式
58066-85-6
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中国地区超过5000个高品质化合物库存
应用领域
Miltefosine是一种广谱抗微生物,抗利什曼原虫,磷脂剂,通过抑制 PI3K/Akt 活性起作用。Miltefosine 是 CTP 磷酸胆碱胞苷基转移酶 (CCT) 的抑制剂
Cas No.: 58066-85-6
名称:
别名:
SMILES: CCCCCCCCCCCCCCCCOP(OCC[N+](C)(C)C)(=O)[O-]
分子式: C21H46NO4P
分子量: 407.57
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Miltefosine is an alkylphosphocholine drug.Miltefosine is an alkylphosphocholine drug with demonstrated activity against various parasite species and cancer cells as well as some pathogenic bacteria and fungi. The pharmacokinetics of miltefosine are mainly characterized by its long residence time in the body, resulting in extensive drug accumulation during treatment and long elimination half-lives. Miltefosine proved to have in vitro ovicidal, schistolarvicidal and lethal activity on adult worms of both Schistosoma species and has considerable molluscicidal activity on their snail hosts. Milt reduces replication of HIV-1 in cocultures of human dendritic cells (DCs) and CD4(+) T cells.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_2566_DC9120_58066-85-6
COA
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