AER-271

产品编号: DC21988 Featured
AER-271
结构式
634913-39-6
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中国地区超过5000个高品质化合物库存
应用领域
AER-271(AER271)是水通道蛋白-4(AQP4)的选择性小分子抑制剂,AER-270的前药具有增强的溶解度; 两种中枢神经系统损伤并发脑水肿模型显示神经功能改善,肿胀减轻。
Cas No.: 634913-39-6
名称: 2-{[3,5-Bis(trifluoromethyl) phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate
别名: AER-271|AER271
SMILES:
分子式: C15H9ClF6NO5P
分子量: 463.653
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility; shows improved neurological outcome and reduced swelling in two models of CNS injury complicated by cerebral edema.Other IndicationPhase 1 Clinical
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_1099_DC21988_634913-39-6
COA
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